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USA
Personne àcontacter Mr. Prime
155 Federal Street, Suite 700, Boston, Massachusetts
Targeted proteomics is a scientific discipline focused on the
quantitative study of specific target proteins, building on the
foundation of general proteomics. Unlike non-targeted proteomics,
this approach selectively chooses ions for the collection of mass
spectrometry data, enabling the analysis of numerous samples with
enhanced accuracy, sensitivity, and reproducibility. Targeted
proteomics is applicable to a range of studies including
post-translational modifications, protein conformations,
protein-protein interactions, dynamics, and the systemic
investigation of metabolic and signaling pathways.
Targeted proteomics quantitative techniques mainly include multiple
reaction monitoring (MRM) and parallel reaction monitoring (PRM).
MRM, also referred to as selected reaction monitoring (SRM),
employs triple quadrupole mass spectrometry (QQQ-MS) to capture
signals conforming to predefined ion criteria, facilitating both
relative and absolute quantification of target proteins. PRM
extends the capabilities of MRM by integrating the high selectivity
of quadrupoles with the superior resolution and precision of the
Orbitrap technology. It measures all fragment ions following the
fragmentation of selected parent ions, offering improved detection
sensitivity and reduced susceptibility to interference.
MtoZ Biolabs leverages a high-throughput mass spectrometry platform
to offer targeted proteomics analysis services, which include:
1. Parallel Reaction Monitoring (PRM) Services
2. MRM/PRM-Based Quantitative Proteomics Analysis
3. Absolute Quantification Analysis （AQUA）
About Us
MtoZ Biolabs is an integrate contract
research organization (CRO) providing advanced proteomics,
metabolomics, bioinformatics, and biopharmaceutical analysis
services to researchers in biochemistry, biotechnology, and
biopharmaceutical fields. The name of MtoZ represents mass to
charge ratio in mass spectrometry analysis, as most of our services
are provided based on our well-established mass spectrometry
platforms. Our services allow for the rapid and efficient
development of research projects, including protein analysis,
proteomics, and metabolomics programs.
MtoZ Biolabs is specialized in quantitative
multiplexed proteomics and metabolomics applications through the
establishment of state-of-the-art mass spectrometry platforms,
coupled with high-performance liquid chromatography technology. We
are committed to developing efficient, and effective tools for
addressing core bioinformatics problems. With a continuing focus on
quality, MtoZ Biolabs is well equipped to help you with your needs
in proteomics, metabolomics, bioinformatics, and biopharmaceutical
research. Our ultimate aim is to provide more rapid,
high-throughput, and cost-effective analysis, with exceptional data
quality and minimal sample.​
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