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Personne àcontacter Ms. Emily
45-1 Ramsey Road, Shirley, New York
This gene encodes a member of the four-and-a-half-LIM-only protein
family. Family members contain two highly conserved, tandemly
arranged, zinc finger domains with four highly conserved cysteines
binding a zinc atom in each zinc finger. This protein is thought to
have a role in the assembly of extracellular membranes. Also, this
gene is down-regulated during transformation of normal myoblasts to
rhabdomyosarcoma cells and the encoded protein may function as a
link between presenilin*2 and an intracellular signaling pathway.
Multiple alternatively spliced variants, encoding the same protein,
have been identified.
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| Pays: | USA |
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