FOXN1 peptide By Creative Diagnostics,
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FOXN1 peptide

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Personne à contacter Ms. Emily

45-1 Ramsey Road, Shirley, New York

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Spécification du produit

  • Brand Name: Creative Diagnostics

La description

Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed.

 

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