INCI name:Palmitoyl
Tripeptide**8 Reference: ECM
Modulinepeptide Source:
synthetic Solubility: soluble in
water Stability: stable Purity:≧*5% Grade:
cosmetic MSDS and
COA:available for your
reference,please contact us Capacity: 1kg per
month Appearance: white
powder 2.Functions:Palmitoyl
Tripeptide**8improvesskinelasticity & firmness and serves as an
anti-inflammatory. 3.Introduction: Palmitoyl
Tripeptide**8 binds with the specific receptor
TGF-bII (TbRII) at the cellular surface. This receptor
phosphorylates the receptor TGF-bI (TbRI) to generate an active
receptors complex so they phosphorylate the protein Smad 2 or Smad
3.Smad 2 or Smad 3 form a complex withthe protein citoplasmatic
Smad 4 and this allows the translocation of the Smad complex into
the nucleus. There, the booster Smad complex binds with specific
sequences of the promoters of the extracellular matrix genes that
activate its expression.
Palmitoyl
Tripeptide**8 is
the key in the regeneration of extracellular matrix as it
stimulates the proteins synthesis in the extracellular matrix,
inhibits the metalloproteinases that degrade the collagen,
stimulates the production of proteases inhibitors and the synthesis
of integrins.
