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South Africa
Personne àcontacter Mr. Jason
56 Wadeville, Germiston, Gauteng
1) Product Name: Best price pyroglutamic acid CAS ******3 l-pyroglutamic acid
2) Active ingredients: l-pyroglutamic acid
3) Specification: ≥*9%
4) Test method: TLC
5) Appearance: white crystalline powder
6) Introduction:
Pyroglutamic acid (also known as PCA, *-oxoproline, pidolic acid, or pyroglutamate for its basic form) is a ubiquitous but little studied natural amino acid derivative in which the free amino group of glutamic acid or glutamine cyclizes to form a lactam.
It is a metabolite in the glutathione cycle that is converted to glutamate by *-oxoprolinase.
Pyroglutamate is found in many proteins including bacteriorhodopsin. N-terminal glutamic acid and glutamine residues can spontaneously cyclize to become pyroglutamate, or enzymatically converted by glutaminyl cyclases. This is one of several forms of blocked N-termini which present a problem for N-terminal sequencing using Edman chemistry, which requires a free primary amino group not present in pyroglutamic acid. The enzyme pyroglutamate aminopeptidase can restore a free N-terminus by cleaving off the pyroglutamate residue.
Pyroglutamic acid, also known as pidolic acid, exists as two distinct enantiomers:
(2R)
or D which happens to be (+) or d
(2S)
or L which happens to be () or l
