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Personne àcontacter Ms. Kitty
ZHONGSHAN ROAD, Wuhan, Hubei
1.Name:Chloramphenicol
2.Cas No.:******7
3.Use:Antibacterial
4.Standards:BP/USP
5.Appearance: A white, grayish-white or yellowish-white, fine,
crystalline powder or fine crystals, needles or elongated
plates, slightly soluble in water, freely soluble in alcohol and
in propylene glycol. A solution in ethanol is
dextrorotatory and a solution in ethyl acetate is
laevorotatory.
6.general info:
Chloramphenicol (INN) is a bactericidal antimicrobial. It is
considered a prototypical broad-spectrum antibiotic, alongside the
tetracycline.
Chloramphenicol is effective against a wide variety of
Gram-positive and Gram-negative bacteria, including most anaerobic
organisms. Due to resistance and safety concerns, it is no longer a
first-line agent for any indication in developed nations, although
it is sometimes used topically for eye infections; nevertheless,
the global problem of advancing bacterial resistance to newer drugs
has led to renewed interest in its use. In low-income countries,
chloramphenicol is still widely used because it is exceedingly
inexpensive and readily available.
The most serious adverse effect associated with chloramphenicol
treatment is bone marrow toxicity, which may occur in two distinct
forms: bone marrow suppression, which is a direct toxic effect of
the drug and is usually reversible, and a plastic anemia, which is
idiosyncratic (rare, unpredictable, and unrelated to dose) and
generally fatal.
