FOB Price
Obtenir le dernier prix200 ~ 300 / Kilogram
|Minimum Order
Localité:
zhejiang
Prix de commande minimale:
Commande minimale:
1 Piece
Packaging Detail:
1kg/bag
Delivery Time:
10 day
Supplying Ability:
100 Kilogram per Day
Payment Type:
T/T, L/C
Personne àcontacter Ms. Bubble
NewYouth Plaza, Hangzhou, Zhejiang
[Product name]: Toosendanin
[Synonym]:
[Plant Source]: CORTEX MELIAE
[Chemical name]: *-isothiocyanato**-(methyl-sulfinyl) butane
[Structural formula]: C*0H*8O*1
[CAS Reg]: *********8
[Molecular weight]: **4.*3
[Specification]: Toosendanin assay: 1.5％,*5%,*8% (HPLC)，or
custom-made according to the customer request
[Main functions]:
Toosendanin (TSN), a tetranortriterpenoid compound from the plant
Melia toosendan, has been reported to protect rats and non-human
primates from the lethal actions of botulinum neurotoxin A
(BoNT/A). TSN was tested in isolated mouse phrenic
nerve-hemidiaphragm preparations against BoNT serotypes A, B and E.
When added prior to toxin, TSN was found to delay the onset of
muscle paralysis with all 3 BoNT serotypes. TSN had little or no
effect on BoNT-induced muscle paralysis when applied *0 min after
BoNT. It is suggested that the antagonist activity of TSN may
result from inhibition of BoNT translocation.
