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Personne àcontacter Mr. Willam
Huming, Xiamen, Fujian
Product name:Rapamycin
CAS:*********9
Molecular Formula:C*1H*9NO*3
Formula Weight:**4.2g/mol
Description:Rapamycin is an immunosuppressant that is used
primarily to prevent the rejection of organ and bone marrow
transplant. It was first described as a potent inhibitor of IL*2
activation of lymphocytes (IC*0 = 5 pM). It is now known that
rapamycin specifically interacts with the cytosolic FK-binding
protein *2 (FKBP*2) to form a complex which inhibits the mammalian
target of rapamycin (mTOR) pathway by directly binding to mTOR
Complex 1 (mTORC1). Rapamycin and other inhibitors of mTORC1
signaling show potential in treating cancer, adipogenesis,
diabetes, tuberous sclerosis, and cardiovascular disease.
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