Prix FOB
Obtenir le dernier prix1 ~ 150 / Kilogram ( Negotiable )
|1 Kilogram Minimum Order
Pays:
China
N ° de modèle:
20%
Prix FOB:
1 ~ 150 / Kilogram ( Negotiable ) Obtenir le dernier prix
Localité:
China
Prix de commande minimale:
1 per Kilogram
Commande minimale:
1 Kilogram
Packaging Detail:
25kg/drum
Heure de livraison:
15 days after payment
Capacité de Fournir:
30 Metric Ton per Month
Payment Type:
T/T, L/C, Western Union
Groupe de produits :
China
Personne àcontacter Ms. Jennifer
No.100 Jinxi Road, Wuxi, Jiangsu
 GABA(Gamma amino butyric acid)
Gamma amino butyric acid powder
Gamma amino butyric acid is the chief inhibitoryneurotransmitter in themammalian central nervous system. It plays a role in regulatingneuronal excitability throughout thenervous system. In humans, GABA is also directly responsible for the regulation ofmuscle tone.
Although chemically it is anamino acid, GABA is rarely referred to as such in the scientific or medical communities, because the term amino acid, used without aqualifier, conventionally refers to thealpha amino acids, which GABA is not, nor is it ever incorporated into aprotein.
Inspastic diplegia in humans, GABA absorption becomes impaired by nerves damaged from the condition'supper motor neuron lesion, which leads tohypertonia of the muscles signaled by those nerves that can no longer absorb GABA.
GABA: Gamma-Amino Butyric Acid
INTRODUCTION:
Gamma-Amino Butyric acid (GABA) is an amino acid which acts as a neurotransmitter in the central nervous system. It inhibits nerve transmission in the brain, calming nervous activity. As a supplement it is sold and promoted for these neurotransmitter effects as a natural tranquilizer. It is also touted as increasing Human Growth Hormone levels and is popular among body builders. The published research supporting any of these promotional claims is weak. Current medical opinion says that GABA taken as a supplement does not reach the brain and has no effect or benefit aside from being a benign placebo.
Many websites claim that the neurotransmitter GABA was discovered in Berlin in ***3, which is an outlandish claim. The concept of neurotransmitters had yet to be conceived of. It is more likely that GABA was isolated and identified as an amino acid in ***3. It was *7 years later, in ***0, that Eugene Roberts and J. Awapara discovered that GABA acted as an inhibitory neurotransmitter.
NEUROTRANSMITTER REVIEW
The nervous system is made up of individual nerve cells called neurons. They serve as the body's wiring. Nerve signals are transmitted through the length of a neuron as an electrical impulse. When a nerve impulse reaches the end of the neuron it can jump over to the next cell using chemical messengers called neurotransmitters.
In the central nervous system, which consists of the brain and the spinal cord, neurotransmitters pass from neuron to neuron. In the peripheral nervous system, which is made up of the nerves that run from the central nervous system to the rest of the body, the chemical signals pass between a neuron and an adjacent muscle or gland cell.
Glutamate and GABA are the most abundant neurotransmitters in the central nervous system, and especially in the cerebral cortex, which is where thinking occurs and sensations are interpreted.
Tiny sacs filled with neurotransmitters are stored at the end of each neuron. When a nerve impulse reaches the cell's end it triggers these sacs to dump the neurotransmitters into the gaps that separate one nerve cell from another. These spaces are called synapses. The neurotransmitters float across the synapse. When they reach the neighboring neuron, the neurotransmitters click into specialized receptor sites much as a key fits into a lock. When enough neurotransmitters attach to the receptors, the neuron, sending an electrical impulse down its length.
GABA'S ROLE IN THE BRAINGABA is made in brain cells from glutamate, and functions as an inhibitory neurotransmitter meaning that it blocks nerve impulses. Glutamate acts as an excitatory neurotransmitter and when bound to adjacent cells encourages them to and send a nerve impulse. GABA does the opposite and tells the adjoining cells not to , not to send an impulse.
Without GABA, nerve cells fire too often and too easily. Anxiety disorders such as panic attacks, seizure disorders, and numerous other conditions including addiction, headaches, Parkinson's syndrome, and cognitive impairment are all related to low GABA activity. GABA hinders the transmission of nerve impulses from one neuron to another. It has a calming or quieting influence. A good example to help understand this effect is caffeine. Caffeine inhibits GABA release. The less GABA, the more nerve transmissions occur. Think what too much coffee feels like: that is the sensation of glutamate without enough GABA.
The reason caffeine does this is that other molecules can bind to the neuron near the GABA binding site and influence GABA's effect. This is how tranquilizing drugs such as Benzodiazepines and barbiturates work. They increase or imitate GABA's effect, inhibiting nerve transmission.
CAN IT WORK?
GABA supplements are promoted as an alternative to these tranquilizing drugs. There's a problem. There is scant evidence that it does anything. Current medical belief is that GABA will not pass the blood brain barrier.
The blood brain barrier is a biologic firewall between the body's general blood circulation and the blood circulation that supplies the brain. It prevents many of the chemicals and drugs which circulate in the blood from reaching the brain. GABA can not cross from the body into the brain. If GABA doesn't reach the brain, can it work? Common medical wisdom says it can't.
So why are so many people buying and taking GABA insisting that it is helpful for its tranquilizing action?
First, it may simply be a placebo. If our thoughts affect our chemistry and physiology, what more susceptible part of our chemistry can there be than the neurotransmitters in our brain that carry thoughts?
Second, it may have some affect that hasn't been reported yet. If taking GABA makes a person feel calmer and more relaxed, perhaps some of it crosses into the brain. Studies on Human Growth Hormone suggest that it can.
Possible Uses of GABA:
The best information I have on clinical use comes from the writing of Eric Braverman and Carl Pfeiffer. Their ***7 book on the clinical use of amino acids is a classic treatise for the practice of nutritional medicine.
Anxiety:
If oral GABA reaches the brain in any significant amount it should act as a tranquilizer. GABA as a neurotransmitter, blocks nerve impulses and slows neuronal transmission. It should make you feel the opposite of a double espresso.
Braverman and Pfeiffer write an anecdotal account of the successful treatment of a forty year old woman suffering from anxiety with **0 mg of GABA a day. They also gave her an undisclosed amount of inositol which we now know is an effective anxiolytic used in treating obsessive compulsive disorder. Was it the GABA or the inositol that helped this patient? Perhaps the combination.
Though this anecdote is inconclusive, using GABA to treat anxiety is the most common and reasonable use.
Will the brain adapt to supplemental GABA? There are no answers to this as no one has proven GABA reaches the brain. Looking at the brain's capacity to change GABA receptor response and its tendency to build up tolerance to drugs which modify GABA, it is possible that a tolerance to oral GABA might develop and withdrawal symptoms might occur. None are reported in the literature to my knowledge.
Additional Information
·Increase in the level of Human Growth Hormones (HGH)
·Induces relaxation and sleep
·Reduces muscle tension
·Reduces stress, anxiety and depression
·Promotes well being
GABA is produced in the human brain and functions as a balancer, maintains balance between the body and the mind in states of excitation. GABA supplement aids several complications including Attention-Deficit Hyperactivity Disorder or ADHD, hypertension or HBP, obesity, insomnia, alcoholism and many more. It is also a great help in treating mental blocks.
GABA supplements are helpful for any active individuals, bodybuilders and athletes. They help in enhancing the bodys muscle mass, which is GABAs conductive anabolic property and its lipotropic property helps in fat reduction and weight loss programs, simultaneously.
| Pays: | China |
| N ° de modèle: | 20% |
| Prix FOB: | 1 ~ 150 / Kilogram ( Negotiable ) Obtenir le dernier prix |
| Localité: | China |
| Prix de commande minimale: | 1 per Kilogram |
| Commande minimale: | 1 Kilogram |
| Packaging Detail: | 25kg/drum |
| Heure de livraison: | 15 days after payment |
| Capacité de Fournir: | 30 Metric Ton per Month |
| Payment Type: | T/T, L/C, Western Union |
| Groupe de produits : | Nutrition supplement |
