Description
1. Sources and
Habitation
Diosmin is a chemical
found in citrus fruits and Scrophularia nodosa, it is also a
semisynthetic drug (modified hesperidin), a member of the flavonoid
family.Â
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It is an oral
phlebotropic drug used in the treatment of venous disease, i.e.,
chronic venous insufficiency (CVI) and hemorrhoidal disease
(HD), in
acute or chronic hemorrhoids, in place of rubber-band ligation,
 in combination with fiber supplement,  or as  an
adjuvant therapy to hemorrhoidectomy, in order to reduce secondary
bleeding. To control internal symptoms of hemorrhoids
(piles), it
is used with hesperidin. Clinical studies have been inconclusive
and no review articles on its use in vascular disease have been
published.
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2. Descriptions and
Specifications of Product
Plant original:
Scrophularia nodosa.
Specifications: *8.0%
Diosmin Test by HPLC
Molecular Formula:
C*8H*2O*5
Molecular Mass:
**8.*4
CAS NO:
*******4Â
3. Indications and
Uses
Diosmin is an
anti-inflammatory and a flavonoid glycoside that reduces venous
hyperpressure.
Diosmin also reduces capillary hyperpermeability and expression of
endothelial adhesion molecules (ICAM1, VCAM1). Diosmin effectively
inhibits the P-glycoprotein (Pgp)-mediated efflux in
cells.
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Diosmin is currently a
prescription medication in some European countries, and is sold as
a nutritional supplement in the United States and the rest of
Europe.
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Diosmin is used for
treating various disorders of blood vessels including hemorrhoids,
varicose veins, poor circulation in the legs (venous
stasis),and
bleeding (hemorrhage) in the eye or gums. It is also used to treat
swelling of the arms (lymphedema) following breast cancer surgery,
and to protect against livertoxicity. It
is often taken in combination with hesperidin, another
plantchechemical.
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4. Safety
Concerns
Caution needed for
pregnant and breastfeeding women. Side-effects: Stomach and
abdominal pain, diarrhea, and headache.
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5. Dosage
Information
The recommended dose is
***0 mg of diosmin plus **0 mg of hesperidin twice daily for 4 days
followed by **0 mg of diosmin and **0 mg of hesperidin twice daily
for 3 days.
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The Information had not
been evaluated by the Food and Drug Administration, only
forreference.
Jessie Lee | Sales Manager
Peace Fortune Enterprise Limited.
T&F: ***************5
M: ***************7 Skype: jessie*****0Â
E: jessieATapeacefortune.com
