Description
1. Sources and
Habitation
Citrus aurantium L,
belonging to the family Rutaceae, is widely distributed in China.
Zhishi, the Chinese traditional name for Citrus
aurantium, has
long been a folk medicine in traditional Chinese medicine (TCMto
improve indigestion and help stimulate the Qi (energy
force).Â
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It also has been a folk
remedy in Italy since the *6th century for fevers like malaria and
as an antiseptic. Recent studies have confirmed that Zhishi,
replacing Ma Huang, can
be used for treatment of obesity without the negative
cardiovascular side effect.Synepherine is the main active compound
found in the fruit of Citrus aurantium, which
is effective in providing the energy boost (caloric expenditure),
aiding the expulsion of wind, warming the stomach, improving the
appetite, and increasing metabolic rate. Citrus
aurantium is theorized to stimulate fat metabolism without the
negative cardiovascular side effects experienced by some people
using Ma Huang. It
is also a mild aromatic expectorant, a nervine and a laxation for
constipatio
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2. Descriptions and
Specifications of Product
Plant original: Citrus
aurantium L.
Specifications: *8.0%
Synephrine by HPLC
Molecular Formula:
C9H*3NO2
Molecular Mass:
**7.*0
CAS No:
******5
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3. Indications and
Uses
In application of
traditional Chinese medical science, it is used to dispel bloating
and a lump in the abdomen and phlegm, and to cureedema,
constipation, gastroptosis, prolapse
of uterus and rectocele.Antitumour,prevent osteoporosis, reduce
cholesterin and protect heart.Nerve protection and prevent diseases
of degeneration of nerve.Relieve
menopausal symptoms of women, improve bone metabolism and protect
cardiovascular system, etc.
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4. Safety
Concerns
Information about the
safety and efficacy of synephrine used as a single drug may be
deduced from the foregoing review of the literature in this
Article. This information is, by and large, not
contended. However,
there exists considerable controversy about the safety and/or
efficacy ofsynephrinecontaining preparations, which are often
confused with synephrine alone, sometimes with
synephrine, and
much has been written about such preparations in the medical
literature and on the Internet. Since this body of literature deals
with mixtures containing synephrine as only one of
several biologicallyactive
components, even, in some cases, without explicit confirmation of
the presence of synephrine, further discussion is outside the scope
of this article.
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5. Dosage
Information
Because synephrine is but
one small component of the Citrus aurantium fruit, a standardized
extract is recommended. A dose of ***0 mg of synephrine per day is
a typical dose found in products providing ******0 mg of a
standardized citrus aurantium extract (**6%
synephrine).
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The Information had not
been evaluated by the Food and Drug Administration, only for
reference
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