Description

**0% Natural Pure Senna Leaf extract

Senna Leaf P.E

Latin Name:Folium Sennae

Botanical Source:Folium sennae

Part Used:Leaf

Appearance:brown powder

Active Ingredient: Sennosides

SpecificationExtract Ratio 4:1 to *0:1; 4%  Sennosides; 8% Sennosides; *0% Sennosides; *0% Sennosides

Test Method: UV

Molecular Formula :C*2H*8O*0

Molecular Weight :**2.*5

CAS NO:******6

[Brief introduction of Senna Leaf extract]

Senna is a shrub found in India, Pakistan, South China and elsewhere. Its name is derived from the Arabic word "sena," and it has been used in ayurvedic and unani medicines since the ninth century. The shrub grows to a height of approximately two feet, with green stems and pods and yellow, scoop-shaped leaves. The alternate leaves are even-pinnate, with four or five pairs of lanceolate or obovate leaflets that are brittle and greyish green in colour. The small yellow flowers are characterised by five spreading clawed petals. The fruit is in an oblong pod about 5cm long. The leaves and pods, or fruit, are used medicinally.

People in northern Africa and southwestern Asia have used senna as a laxative for centuries. Senna was traditionally considered a "cleansing" herb because of its cathartic properties. More modern studies have found that senna is useful in treating constipation, whether it is caused by pharmaceuticals or natural means. In addition, the leaves were sometimes made into a paste and applied to various skin diseases. Ringworm and acne were both treated in this way.

Function

The active substances in senna leaves are called sennosides. These molecules are converted by bacteria in the colon into another substance, rhein-anthrone, which has two beneficial effects, colon activity stimulation(which speeds bowel movements and improves digestion) and increased fluid secretion. The laxative effect of sennosides and their active metabolite, rhein anthrone, is due to inhibition of water and electrolyte absorption from the large intestine, which increases the volume and pressure of the intestinal contents. This will stimulate the colon motility resulting in propulsive contractions. In addition, stimulation of active chloride secretion increases water and electrolyte content of the intestine. These changes in active electrolyte transport are depend on calcium in the serosal surface. The laxative action of Sennosides are partially via stimulation of colonic fluid and electrolyte secretion, and this secretion is mediated by stimulation of endogenous prostaglandin formation. Sennosides may be prepared as an enema or suppository or combined with a Stool Softener or Bulk Forming Fiber Laxative to form a Combination Laxative.

Chemistry

Senna leaf contains: Approximately 3% dianthrone glycosides (sennosides A, A1, B, C, D, E, F & G ); and small amounts of anthraquinones including aloe-emodin and rhein *-glucoside; approximately *0% mucilage; tannins; and flavonoids. The extract is standardized to 8% sennosides.This product is mainly composed of Sennosides.

Dosage:

******0 mg at bedtime as purgative.

Safety:  

Sennosides are strong purgative that should be taken with care and in proper dosage, especially for pregnant, menstruating, or postpartum women. It cannot be used where there is inflammation in the G.I. Tract because of irritation. The irritant effect upon the intestinal membrane may cause griping, pain or nausea, along with liquid .stools or diarrhea for overdose.

[Package]

1KG : Packed in  Aluminum foil bag with pharma-grade polybags;

5KG : Packed in Aluminum foil bag with two pharma-grade polybags; or drum with pharma-grade polybag. Drum size:*0**0CM. Drum Weight:1.5KG

*0KG: Packed in  Aluminum foil bag with two pharma-grade polybags;

*5KG: Packed in HDPE drums/ Hardboard cartons with pharma-grade polybag.

Carton size:D*8 CM * H*2CM. Drum gross weight:2.8kgs

[Minimum quantity-MOQ]

1kg will be welcomed as the sample, but the less you buy, more expensive the price and transportation fees will be.

[Transport and Payment]

1. Small package send by EMS, UPS, FedEx, DHL, etc.

2. Cargo send by Air or By Sea is all available when the purchasing weight is allowed

3. Delivery time about 7 working days By Air, *0 days By sea.

4. Payment available for T/T, Paypal, etc., Paypal with little money for samples will be the one we suggested.

[Delivery cost]

The price of the transportation fees need to consider the transportation ways and fees.

[About Manufacturer Kang Biotech]

History: “Hunan Kang Biotech” is a subsidiary of “Hunan Kang Pharmaceutical Group”, which engaged in the natural ingredients' research & development (R & D), production and selling. Providing the high-quality natural materials for manufacturers and enterprises of botanical drug, health food, beverage, cosmetic etc.

Certification: Our company is equipped with UV/HPLC/GC/AA and other modern analyzing instruments to assure high quality. Our factory have passed GMP in Aug.*0.***0, Certificate No.:J***1

Factory: Hunan Kang Biotech’s factory covers an area of **0 Acres, and the production workshop is designed according to GMP standard.

[Why Chose Kang Biotech]

1)Free sample(****0g or enough to detection) and Unconditional assume responds

2)**0% Natural product, without any synthesized ingredient

3) Manufacturer direct supply, provide OEM, R&D service

4)GMPs,Gsp

5) Leading plant extract manufacturer in China