Description

Ginkgo Biloba P.E (Flavoglycosides)

[Product Name]: Ginkgo Biloba Extract

[Plant Origin]: Ginkgoaceae, Ginkgo

[Latin Name]: Folium Ginkgo

[Part Used]: Leaf

[Active ingredient]:Flavoglycosides*4% & Terpene Lactones6%

[CAS No. ]:*********6

[Assay]:HPLC

[Molecular Formula]:C*0H*4O*0

[Molecular Weight]:**4.****6

[Appearance]: Brown to light yellow fine powder

[Solubility]:dissolved in ethyl acetate, methanol, ethanol, dimethyl sulfoxide and other solvents.

[Melting Point]: **5°C***7°C

Introduction ofGinkgo Biloba P.E

Ginkgo biloba is one of the world\'s oldest living tree species. The earliest record of the use of Ginkgo Biloba leaves as a medicine is mentioned in the Chinese Materia Medical Shen Nung Pen Tsao Ching, as an aid for blood circulation and disorders of lungs. They are also used for chilblains and as a wound plaster. In ***2, Japanese Furukawa isolated ginkgolides for the first time, which were further investigated for their chemical structure in ***6. Dr. Willmar Schwabe Company produced the first extract from leaves in ***5. With the advent and popularization of antioxidant theory in recent years, Ginkgo biloba has rapidly become one of the most widely used health supplements in the world.

Function:

The leaves are still used in Chinese medicine to treat memory loss, stomach pain, dysentery, high blood pressure and anxiety as well as other respiratory problems like asthma, bronchitis, and poor circulation. The active component of Ginkgo biloba is the terpene fraction, which consists of ginkgolides and bilobalides. These ginkgo flavone-glycosides have powerful antioxidant and free radical scavenging capability.

1. Circulation Improvement:

Ginkgo biloba extract increases circulation to both the brain and extremities of the body. One of the primary protective effects of the ginkgolides are their ability to inhibit a substance known as platelet-activating factor (PAF). PAF is a mediator released from cells that causes platelets to aggregate (clump together). High amounts of PAF are associated with damage to nerve cells, poor blood flow to the central nervous system, inflammatory conditions, and bronchial constrictions. Much like free radicals, higher PAF levels are also associated with aging. Ginkgolides and bilobalide protect nerve cells in the central nervous system from damage during periods of ischemia (lack of oxygen to tissues in the body). This effect may be supportive for persons who have suffered a stroke. In addition to inhibiting platelet stickiness, ginkgo biloba extract regulates the tone and elasticity of blood vessels. In other words, it makes circulation more efficient. This improvement in circulation efficiency extends to both large vessels (arteries) and smaller vessels (capillaries) in the circulatory system.

2. Antioxidant Properties:

Ginkgo biloba extract may have antioxidant properties in the brain, retina of the eye, and the cardiovascular system. Its antioxidant activity in the brain and central nervous system may help prevent age-related declines in brain function. Ginkgo biloba extract for antioxidant activity in the brain is of particular interest. The brain and central nervous system are particularly susceptible to free radical attack. Free radical damage in the brain is widely accepted as being a contributing factor in many disorders associated with aging, including Alzheimer\'s disease.

3. Anti-Aging Properties

Ginkgo increases blood flow to the brain and has excellent restorative effects on the nervous system. Hundreds of scientific studies, involving tens of thousands of patients, attest to the effectiveness of Ginkgo biloba extract for the many problems associated with cerebral vascular insufficiency and impaired mental performance in elderly patients.

Ginkgo is of benefit for many of the presumed symptoms of aging such as:

Anxiety and depression 

Memory impairment 

Poor concentration, decreased alertness

Diminished intellectual capacity 

Vertigo, headache 

Tinnitus (ringing in the ears) 

Macular degeneration ( the most common cause of blindness in adults) 

Inner ear disturbances (which can cause partial deafness) 

Poor circulation in the extremities 

Impotence due to impaired penile blood flow 

4. Dementia, Alzheimer\'s Disease and Memory Improvement

Researchers recently reviewed all of the high-quality published studies on ginkgo and mild memory impairment, and concluded that ginkgo was significantly more effective than placebo in enhancing memory and cognitive function.

Ginkgo is widely used in Europe for treating dementia. The reason that ginkgo is thought to be helpful for preventing or treating these brain disorders is because it improves blood flow in the brain and because of its antioxidant properties. Although many of the clinical trials have been scientifically flawed, the evidence that ginkgo may improve thinking, learning, and memory in people with Alzheimer\'s disease (AD) has been highly promising.

Clinical studies suggest that ginkgo provides the following benefits for people with AD:

Improvement in thinking, learning, and memory

Improvement in activities of daily living

Improvement in social behavior

Fewer feelings of depression

5. PMS Symptoms

One double-blind placebo-controlled study evaluated the benefits of Ginkgo biloba extract for women with PMS symptoms. This trial enrolled **3 women, *8 to *5 years of age, and followed them for two menstrual cycles. Each woman received either the ginkgo extract (*0 mg twice daily) or placebo on day *6 of the first cycle. Treatment was continued until day 5 of the next cycle, and resumed again on day *6 of that cycle. The results were impressive. As compared to placebo, ginkgo significantly relieved major symptoms of PMS, especially breast pain and emotional disturbance.

6. Sexual Dysfunction

Although there is no double-blind evidence at the time of this writing, case reports and open studies suggest that ginkgo can reverse the sexual dysfunction caused by drugs in the Prozac family as well as other types of antidepressant medications.

7. Eye problems

The flavonoids found in ginkgo may help halt or lessen some retinal problems. Retinal damage has a number of potential causes, including diabetes and macular degeneration. Macular degeneration (often called age-related macular degeneration or ARMD) is a progressive, degenerative eye disease that tends to affect older adults and is the number one cause of blindness in the United States. Studies suggest that gingko may help preserve vision in those with ARMD.

Dosage:

The general consensus is that for the treatment of micro-circulation problems in the extremities, including vertigo, tinnitus and intermittent claudication, a dosage of ******0 mg per day is suitable. For treatment of dementia, mild depression, and improvement of cognitive abilities, higher doses (about **0 mg/day) are recommended. For best results, daily dosage is typically split into **3 divided doses. Be sure to look for an extract standardized to at least *4% ginkgo flavone glycosides and 6% terpene lactones – because this is the type of extract that has been shown to be effective in virtually every clinical trial.

Safety:

Ginkgo appears to be safe. Extremely high doses have been given to animals for long periods of time without serious consequences. In all the clinical trials of ginkgo up through ***1 combined, involving a total of almost *0,**0 participants, the incidence of side effects produced by ginkgo extract was extremely small. There were *1 cases of gastrointestinal discomfort, and even fewer cases of headaches, dizziness, and allergic skin reactions.

Chemistry:

This product is composed of some kinds of flavones and Ginkgoslides mainly.

Applications ofGinkgo Biloba P.E

1. Applied in pharmaceutical field, it can be used for treating stomach ache, diarrhea, high blood pressure, nervousand respiratory diseases such as asthma, bronchitis

2. Applied in health product field, it can effectively reduce breast pain and emotional instability

3. Functional foods areas: protecting vascular endothelial tissue, regulating blood lipids

[Package]

1KG : Packed in  Aluminum foil bag with pharma-grade polybags;

5KG : Packed in Aluminum foil bag with two pharma-grade polybags; or drum with pharma-grade polybag. Drum size:*0**0CM. Drum Weight:1.5KG

*0KG: Packed in  Aluminum foil bag with two pharma-grade polybags;

*5KG: Packed in HDPE drums/ Hardboard cartons with pharma-grade polybag.

Carton size:D*8 CM * H*2CM. Drum gross weight:2.8kgs

[Minimum quantity-MOQ]

1kg will be welcomed as the sample, but the less you buy, more expensive the price and transportation fees will be.

[Transport and Payment]

1. Small package send by EMS, UPS, FedEx, DHL, etc.

2. Cargo send by Air or By Sea is all available when the purchasing weight is allowed

3. Delivery time about 7 working days By Air, *0 days By sea.

4. Payment available for T/T, Paypal, etc., Paypal with little money for samples will be the one we suggested.

[Delivery cost]

The price of the transportation fees need to consider the transportation ways and fees.

[About Manufacturer Kang Biotech]

History: “Hunan Kang Biotech” is a subsidiary of “Hunan Kang Pharmaceutical Group”, which engaged in the natural ingredients\' research & development (R & D), production and selling. Providing the high-quality natural materials for manufacturers and enterprises of botanical drug, health food, beverage, cosmetic etc.

Certification: Our company is equipped with UV/HPLC/GC/AA and other modern analyzing instruments to assure high quality. Our factory have passed GMP in Aug.*0.***0, Certificate No.:J***1

Factory: Hunan Kang Biotech’s factory covers an area of **0 Acres, and the production workshop is designed according to GMP standard.

[Why Chose Kang Biotech]

1)Free sample(****0g or enough to detection) and Unconditional assume respond

2)**0% Natural product, without any synthesize ingredient

3)Manufacturer direct supply, provide OEM, R&D service

4)GMPs,Gsp

5)Leading plant extract manufacturer in China