Description
Ursolic acid is a pentacyclic triterpene acid,
used in cosmetics, that is also capable of inhibiting various types
of cancer cells by inhibiting the STAT3 activation pathway and
human fibrosarcoma cells by reducing the expression of matrix
metalloproteinase*9 by acting through the glucocorticoid
receptor.
Ursolic acid is also known as Prunol, Malol, Urson, beta-Ursolic
acid, NSC***0, CCRIS ***3, CHEBI:***8, TOS-BB****6, and
3beta-Hydroxyurs***-en***-oic acid. As medicine it is well
tolerated and can be used topically and orally.
Ursolic acid is present in many plants, including apples, basil,
bilberries, cranberries, elder flower, peppermint, lavender,
oregano, thyme, hawthorn, prunes.
PHARMACOLOGICAL ACTIVITIES
Contemporary scientific research which led to the isolation and
identification of ursolic acid revealed and confirmed that several
pharmacological effects, such as antitumor, hepatoprotective,
anti-inflammatory (oral and topical), anti-aging,,antiulcer,
antimicrobial, anti-hyperlipidemic, sedation, antioxidation and
antiviral, hair growth stimulant,can be attributed to ursolic acid
which is widely used in medicine.It can inhibit Elastase. However,
its anti-inflammatory (topical), antitumor (skin cancer), and
antimicrobial properties make it useful in cosmetic
applications.
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How to
take ursolic acid?
The
only dose from which to work from is *0mg/kg
bodyweight.
Note:Â Do not confuse with usnic
acid
