Description
Emodin Anthraquinones represent a large family of
compounds having diverse biological properties. Emodin
(1,3,*-trihydroxy**-methylanthraquinone) is a naturally occurring
anthraquinone present in the roots and barks of numerous plants,
molds, and lichens, and an active ingredient of various Chinese
herbs
Pharmacology
Emodin is being studied as a
potential agent that could reduce the impact of type 2 diabetes. It
is a potent selective inhibitor of the
enzyme *1β-HSD1. In studies
in obese mice, emodin limits the effect of glucocorticoids and
may therefore ameliorate diabetes and insulin
resistance.
Pharmacological studies have
demonstrated that emodin when isolated from rhubarb exhibits
anti-cancer effects on several human cancers including human
pancreatic cancer. Emodin in rhubarb extracts may also have
neuroprotective properties against glutamate toxicity, but in other
studies it seems to increase inflammation and have other possible
neurotoxic effects.
Aloe-emodin
(1,3,*-trihydroxyanthraquinone) is a variety of emodin found in
Socotrine, Barbados, and
Zanzibar aloes, but not in Natal aloes
Main
Functions
1. Anti-tumor. The Emodin has effective restrain to cell
proliferation of hepatoma, lung tumor, bladder tumor and so on.
2. Protecting the Liver. Emodin protect the liver damage caused by
carbon tetrachloride, and has a effective restrain to the Hepatitis
B.
3. Anti-renal fibrosis. Emodin can restrain the division and
proliferation of the HRIF. It can also result in the cell death by
improving the level of C-MYC protein.
4. Antibiotic Action. Emodin has the inhibitory action of
Staphylococcus aureus, Staphylococcus aureus(S. aureus) and
Pseudomonas aeruginosa.
