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Personne àcontacter Mr. Shun
Linchi Industrial Zone, Zouping County, Shandong
Name: Sulbactam, Sulbactam acid (base)
Molecular Formula: C8H*1NO5S
Molecular Weight: **3.*4
CAS Registry Number: *********8
EINECS: ********2
Sulbactam is an irreversible inhibitor of beta-lactamase; It binds
the enzyme and does not allow it to interact with the
antibiotic.
Sulbactam is able to inhibit the most common forms of
beta-lactamase but is not able to interact with the ampC
cephalosporinase. Thus, it confers little protection against
bacteria such as Pseudomonas aeruginosa, Citrobacter, Enterobacter,
and Serratia, which often express this gene.
In the United States, sulbactam is combined to form
cefoperazone/sulbactam and ampicillin/sulbactam. It does possess
some antibacterial activity when administered alone, but it is too
weak to have any clinical importance. Its use in the UK is
restricted to hospitals.
