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Minimum Order
Localité:
Zhuhai
Prix de commande minimale:
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Commande minimale:
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Packaging Detail:
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Delivery Time:
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Supplying Ability:
10000 Acre per Day
Payment Type:
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China
Personne àcontacter Ms. Sanjay
6/F,Building B,108 Xinghua Road, Xiangzhou, Zhuhai, Guangdong
FOB Rapid Test Card is an immunochromatographic in vitro assay
for qualitative determination of human hemoglobin in feces.
Hemoglobin in feces is an indication of internal bleedings
associated with pathological conditions of gastrointestinal tract
such as colon polyps, colorectal carcinoma, ulcerative colitis, and
crohn?s disease
Colorectal cancer is the third most common cancer in the world.
?Fecal occult blood? is generally defined as a blood loss of less
than *0 ml/d. The appearance of occult blood in human fecal
specimen is often associated with gastrointestinal diseases, which
might cause colorectal cancer if not treated promptly and properly.
Traditional guaiac-based method lacks sensitivity and specificity,
and has diet restriction prior to testing.
FOB Rapid Test Card uses technology of lateral flow double antibody
sandwich assay. The test is more sensitive and more specific than
the traditional guaiac assay does. It is easier to interpret the
result. In addition, unlike the guaiac assays, the accuracy of the
test is not affected by the diet of the patients.
FOB Rapid Test Card is composed of two units, a fecal collection
tube and a test device. Fecal specimen is collected in the
collection tube containing sample extraction buffer and then added
to the test device. When the sample is added to sample pad, it
moves through the conjugate pad and mobilizes gold anti-human
hemoglobin antibody conjugate that is coated on the conjugate pad.
The mixture moves along the membrane by capillary action and reacts
with anti-human hemoglobin antibody that is coated on the test
region. If hemoglobin is present of *0 ng/ml or greater, the result
is the formation of a colored band in the test region. If there is
no hemoglobin in the sample, the test area will remain colorless.
The sample continues to move to the control area where Goat
anti-mouse IgG antibody will capture gold-sample antibody conjugate
to form a pink to purple color, indicating the test is worki
Colorectal cancer is a leading cause of illness and death in the
Western world. Screening with fecal occult blood tests is based on
the concept that important target colonic neoplasm, such as
early-stage cancer and large adenomatous polyps, will bleed, for
which may be detected by an occult blood test. When
gastrointestinal blood is lost, the stool will contain a
combination of intact or nearly intact hemoglobin, intact heme, and
heme-derived porphyrins in amounts that depend on the site, the
amount of bleeding and the transit time through the gut.
Immunochemical tests detect intact or nearly intact human
hemoglobin, being a very specific technique to detect the loss of
blood from the lower intestine, because blood from lower sites is
less degraded during transit. The hemoglogin is unstable in feces,
leading to false negative results. The detection of fecal
transferrin, which is more stable than hemoglobin, provides an
alternative way of diagnosing the disease in the upper digestive
tract.
Transferrin is a blood-derived component that may be leaked into gastrointestinal tract and then discharged with the feces in gastrointestinal bleeding diseases. Transferrin is stable in feces and a good marker to detect loss of blood from the upper and lower intestine (gastrointestinal bleeding). This immunochromatographic assay detects human hemoglobin and human transferrin in stool samples simultaneously, by obtaining more accurate testing results.
