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PVP-IODINE (povidone-iodine) disinfection drugs
Introduction
As a non-metallic elements necessary by French scientists in ***2
discovered Courtois, due to its deep purple steam in ***4 by the
Cuy-Lussac name, derived from the Greek word "ioeides", meaning
purple.
In medical practice, iodine was first used as a therapeutic drug
for bronchitis (Halliday, ***1), ***9 was first used as a cure for
wounds (Davis, ***9, Boinet***5). ***0, with "iodine" in the form
approved by the U.S. Pharmacopeia. ***4, iodine was found to be one
of the most effective sterilization, but its unpleasant odor and
stain the skin making it unsuitable for practical use. In addition,
iodine to human and animal tissue irritation, and iodine solution
is unstable.
To the end of the last century, scientists have developed a series
of iodine compounds and preparations, used to overcome the side
effects of iodine, such as in an open wound causing pain and
possible allergic reactions. Aimed at reducing the bactericidal
effect is not significant in the case to avoid incompatibility.
Therefore iodine carrier such as an ISP's PVP iodine, has become
an ideal application form.
The general characteristics and advantages
Fifties, PVP iodine (povidone-iodine) as a fungicide used in the
pharmaceutical market for a broad spectrum of pathogenic
microorganisms, it is as effective as iodine itself. And iodine is
different, PVP iodine less irritating to the skin and does not
dissolve iodide or ethanol. In addition, PVP iodine stains can be
washed. Early promotional materials will PVP iodine as "moderate
iodine", because of its safety. Also, products containing PVP
iodine iodine product does not require toxic label.
PVP iodine in human and veterinary medicine can be used, used to
kill a variety of bacteria, germs, fungi, protozoa and yeast, for
the suppression of certain insects are equally effective, but not
PVP iodine resistant coverage.
Meanwhile, compared with the conventional iodine, PVP iodine safer,
easier to use and lower systemic toxicity. The iodine solution is
different, it does not sensitization, the use in the wound and
mucous membranes does not cause pain. PVP iodine formed thin film
to protect the open wounds, and this film can be washed with water,
will not stain the skin for a long time, fiber or hard surface. PVP
iodine particularly easy to use, because it is soluble in water and
organic solvents such as ethanol. It can be in powder, tablets,
troches, solutions, lotions, gels, ointments, creams, mousses or
sprays carried formula.
PVP iodine prolonged non-specific antibacterial activity of
microorganisms on the surface with superior effect on the treatment
of mixed infections are particularly effective. PVP iodine has been
demonstrated clinically in human and veterinary medicine in a
variety of external validity.
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