Prix FOB
Obtenir le dernier prix0.15 ~ 0.3 USD /
|10000 Box Minimum Order
Pays:
China
N ° de modèle:
-
Prix FOB:
0.15 ~ 0.3 USD / Obtenir le dernier prix
Localité:
China (Mainland)
Prix de commande minimale:
0.15
Commande minimale:
10000 Box
Packaging Detail:
cartons
Heure de livraison:
40days
Capacité de Fournir:
10000000 Box per Month
Payment Type:
L/C, T/T
Groupe de produits :
Personne àcontacter Mr. Kevin
No. 35 Huitong Road, Shijiazhuang, China, Shijiazhuang, Hebei
Dextrose and Sodium Chloride Injection is used for parenteral
replenishment of fluid,
Â
Product Name: Dextrose and Sodium Chloride Injection, Dextrose and Sodium Chloride Infusion
Product Description :A clear, colourless liquid.
Strength:Â (1)**0ml:Glucose:*5g/Sodium Chloride:4.5g; (2)**0ml:Glucose:*2.5g/Sodium Chloride:2.*5g; (3)**0ml:Glucose:5g/Sodium Chloride:0.9g
INN or Generic Name:Dextrose and Sodium Chloride
Injection
Pharmaceutical Dosage Form:Â Â injection
Port:Any port (depends on
requests)Â Â Â Â Â
 Certificate:GMP
Exporting Region:Areas which GMP is applicable
Therapeutic indications
Intravenous solutions containing Dextrose and Sodium Chloride are indicated for parenteral replenishment of fluid, minimal carbohydrate calories, and sodium chloride as required by the clinical condition of the patient.
Posology and method of administration
The dose is dependent upon the age, weight and clinical condition
of the patient.
As reported in the literature, the dosage and constant infusion
rate of intravenous dextrose must be selected with caution in
pediatric patients, particularly neonates and low birth weight
infants, because of the increased risk of
hyperglycemia/hypoglycemia.
Parenteral drug products should be inspected visually for
particulate matter and discoloration prior to administration,
whenever solution and container permit. See PRECAUTIONS.
Drug Interactions
Additives may be incompatible. Consult with pharmacist, if
available. When introducing additives, use aseptic technique, mix
thoroughly and do not store.
Contraindications:
Solutions containing dextrose may be contraindicated in patients with known allergy to corn or corn products.
Special warning and precautions for use:
Warnings
Solutions containing sodium ions should be used with great care,
if at all, in patients with congestive heart failure, severe
renal insufficiency and in clinical states in which there exists
edema with sodium retention.
Excessive administration of potassium-free solutions may result
in significant hypokalemia.
In patients with diminished renal function, administration of
solutions containing sodium ions may result in sodium
retention.
The intravenous administration of these solutions can cause fluid
and/or solute overloading resulting in dilution of serum
electrolyte concentrations, overhydration, congested states or
pulmonary edema.
The risk of dilutional states is inversely proportional to the
electrolyte concentrations of administered parenteral solutions.
The risk of solute overload causing congested states with
peripheral and pulmonary edema is directly proportional to the
electrolyte concentrations of such solutions.
Clinical evaluation and periodic laboratory determinations are
necessary to monitor changes in fluid balance, electrolyte
concentrations and acid-base balance during prolonged parenteral
therapy or whenever the condition of the patient warrants such
evaluation.
Solutions containing dextrose should be used with caution in
patients with known subclinical or overt diabetes mellitus.
Caution must be exercised in the administration of parenteral
fluids, especially those containing sodium ions to patients
receiving corticosteroids or corticotropin.
Do not administer unless solution is clear and container is
undamaged. Discard unused portion.
Interaction with other medicinal products and other forms of Interactions
None known
 Pregnancy and lactation
Animal reproduction studies have not been conducted with dextrose or sodium chloride. It is also not known whether dextrose or sodium chloride can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Dextrose or sodium chloride should be given to a pregnant woman only if clearly needed.
Pediatric Use.
The safety and effectiveness in the pediatric population are
based on the similarity of the clinical conditions of the
pediatric and adult populations. In neonates or very small
infants, the volume of fluid may affect fluid and electrolyte
balance.
Frequent monitoring of serum glucose concentrations is required
when dextrose is prescribed to pediatric patients, particularly
neonates and low birth weight infants.
In very low birth weight infants, excessive or rapid
administration of dextrose injection may result in increased
serum osmolality and possible intracerebral hemorrhage.
An evaluation of current literature revealed no clinical experience identifying differences in response between elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy. Sodium ions are known to be substantially excreted by the kidney, and the risk of toxic reactions may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function.
Effects on ability to drive and use machine
Not applicable.
Undesirable effects
Reactions which may occur because of the solution or the
technique of administration include febrile response, infection
at the site of injection, venous thrombosis or phlebitis
extending from the site of injection, extravasation and
hypervolemia.
If an adverse reaction does occur, discontinue the infusion,
evaluate the patient, institute appropriate therapeutic
countermeasures and save the remainder of the fluid for
examination if deemed necessary.
Overdose and special antidotes
In the event of overhydration or solute overload, re-evaluate the patient and institute appropriate corrective measures. See WARNINGS, PRECAUTIONS, and ADVERSE REACTIONS.
Pharmacological Properties
:
Pharmacodynamic Properties
When administered intravenously, these solutions provide a source
of water, carbohydrate and electrolytes.
Solutions which provide combinations of hypotonic or isotonic
concentrations of dextrose and of sodium chloride are suitable
for parenteral maintenance or replacement of water and
electrolyte requirements with minimal carbohydrate calories.
Solutions containing carbohydrate in the form of dextrose restore
blood glucose levels and provide calories. Carbohydrate in the
form of dextrose may aid in minimizing liver glycogen depletion
and exerts a protein-sparing action. Dextrose injected
parenterally undergoes oxidation to carbon dioxide and water.
Sodium chloride in water dissociates to provide sodium (Na+) and
chloride (Cl¯) ions. Sodium (Na+) is the principal cation of the
extracellular fluid and plays a large part in the therapy of
fluid and electrolyte disturbances. Chloride (Cl¯) has an
integral role in buffering action when oxygen and carbon dioxide
exchange occurs in the red blood cells. The distribution and
excretion of sodium (Na+) and chloride (Cl¯) are largely under
the control of the kidney which maintains a balance between
intake and output.
| Pays: | China |
| N ° de modèle: | - |
| Prix FOB: | 0.15 ~ 0.3 / Obtenir le dernier prix |
| Localité: | China (Mainland) |
| Prix de commande minimale: | 0.15 |
| Commande minimale: | 10000 Box |
| Packaging Detail: | cartons |
| Heure de livraison: | 40days |
| Capacité de Fournir: | 10000000 Box per Month |
| Payment Type: | L/C, T/T |
| Groupe de produits : | generic |
