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Personne àcontacter Ms. First Name
NO. 518 Laodong East Road, Changzhou, Jiangsu
Tofacitnib, Pheumatoid arthritis, in house grade.
Tofacitinib is an inhibitor of Janus kinases, a group of
intracellular enzymes involved in signalling pathways that affect
hematopoiesis and immune cell function. It is approved by the FDA
for treatment of moderate to severe rheumatoid arthritis that
responds inadequately to methotrexate or in those who are
intolerant to methotrexate. Besides rheumatoid arthritis,
tofacitinib has also been studied in clinical trials for the
prevention of organ transplant rejection, and is currently under
investigation for the treatment of psoriasis. Known adverse effects
include nausea and headache as well as more serious immunologic and
hematological adverse effects.
Pays: | China |
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