Specification
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1.
Introduction of Sodium ascorbate
Sodium ascorbate is a more bioavailable[citation needed] form of
vitamin C that is an alternative to taking ascorbic acid as a
supplement. The IUPAC Name of it is Sodium
(2R)**-[(1S)*1,*-dihydroxyethyl]**-hydroxy**-oxo*2H-furan**-olateÂ
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2.
Properties of Sodium ascorbate
H-Bond Donor: 3Â
H-Bond Acceptor: 6Â
Rotatable Bond Count: 2Â
Tautomer Count: 2Â
Exact Mass: **8.*****3Â
MonoIsotopic Mass **8.*****3Â
Topological Polar Surface Area: **0Â
Heavy Atom Count: *3Â
Complexity: **7Â
Solubility: H2O: *0 mg/mLÂ
Water Solubility: **0 g/L (*0 °C)Â
Melting Point: **0 °C (dec.)(lit.)
alpha: **4 °(C=1, H2O *5 °C)Â
Refractive index: **5.5 °(C=*0, H2O)
Flash Point: **8.2 °C Â
Enthalpy of Vaporization: *5.*8 kJ/mol Â
Boiling Point: **2.7 °C at **0 mmHg Â
Vapour Pressure of Sodium ascorbate: 1.*2E**4 mmHg at *5 °C
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3.
Preparation of Sodium ascorbate
Sodium ascorbate is produced by dissolving ascorbic acid in water
and adding an equivalent amount of sodium bicarbonate. After
cessation of effervescence, the sodium ascorbate is precipitated
by the addition of isopropanol.
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4. Use of
Sodium ascorbate
As a food additive, it has the E number E**1 and is used as an
antioxidant and an acidity regulator. Sodium ascorbate can
reverse the development of atherosclerotic disease, helps in
heart attack prevention. In addition sodium ascorbate plays a
significant role in the elimination of chronic and acute
infections. Moreover, it is considered to be an anti-cancer
agent. Sodium ascorbate produces cytotoxic effect in an array of
malignant cell lines, which include melanoma cells that are
particularly susceptible.Â
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5.
Side-effects of sodium ascorbate
The common side-effects that persist or become troublesome when
using sodium ascorbate, especially in a liquid form as
injections, include burning, stinging, pain, or swelling at the
injection site. Severe allergic reactions include rash; itching;
difficult breathing; hives; tightness in the chest; swelling of
the mouth, face, lips, or tongue; bone pain; muscle weakness;
severe or persistent diarrhea; mental or mood changes.
