Piceatannol By Chongqing Tingyi Biotechnology Co, Ltd,
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Piceatannol

( Negotiable )

|

1 Gram Minimum Order

Pays:

China

N ° de modèle:

-

Prix FOB:

( Negotiable ) Obtenir le dernier prix

Localité:

Wuhan, China

Prix de commande minimale:

-

Commande minimale:

1 Gram

Packaging Detail:

-

Heure de livraison:

-

Capacité de Fournir:

100 Kilogram per Month

Payment Type:

Western Union, Money Gram, Other

Groupe de produits :

-

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Membre gratuit

Personne à contacter Clara

Chongqing, Chongqing

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Spécification du produit

  • MF: C14H12O4
  • Grade Standard: Feed Grade
  • Usage: Weight Loss
  • Brand Name: Tingyi
  • Purity (%): 99%

La description

 

Description

 

Piceatannol is a chemical compound with similar structure to resveratrol, being widely existed in vegetables such as grapes, blueberries and passion fruit. It is capable of inhibiting the growth of immature adipocytes, so as to achieve the purpose of weight loss. In addition, it also helps prevent cancer, heart disease and neurological diseases.


In early April ***2, researchers in Purdue University has published a new study in journal, finding that piceatannol can delay the production of new fat cells, and inhibit the growth of immature fat cells into mature cells, which can help control the obesity. The researchers also claim that while this study shows that red wine helps to lose weight, further research is needed to improve the stability and solubility of the white fat to maximize its effect.


Laboratory preparation: 3, *-dimethoxybenzyl alcohol is used as the starting material; to obtain the target product; the raw material needs to undergo bromination, Arbuzov rearrangement reaction, Wittig-Horner reaction and demethylation reaction.

 

 

Biological Activity Piceatannol is a selective Syk inhibitor with IC*0 of ~*0 M. Piceatannol is a plant secondary natural product which inhibits the purified thymocyte p*0 kinase (the catalytic fragment of Syk), by competing for the peptide or protein substrate binding site with Ki of *5 M. Piceatannol also inhibits the activity of the p*6lck protein-tyrosine kinase in LSTRA cell membranes or intact cells. Piceatannol preferentially inhibits the activity of Syk in comparison to Lyn in in vitro kinase assays. Selective inhibition of Syk by Piceatannol blocks receptor-mediated down-stream cellular responses (inositol 1,4,*-trisphosphate production, secretion, ruffling, and spreading). Piceatannol is a potent inducer of apoptosis in the lymphoma cell line BJAB by causing a concentration-dependent activation of caspase*3 and mitochondrial permeability transition.

 

Piceatannol but not resveratrol is a very efficient inducer of apoptosis in ex vivo assay with leukemic lymphoblasts of *1 patients suffering from childhood lymphoblastic leukemia (ALL). Piceatannol inhibits TNF-induced NF-B activation and NF-B-mediated gene expression through suppression of IB kinase and p*5 phosphorylation.

 

Piceatannol inhibits the growth of colorectal cancer cell lines and arrests Caco*2 cells in the S phase of the cell cycle. Sequential treatment with Piceatannol and Ara-C yields synergistic growth inhibitory effects against HL**0 cells because of remarkably increased Ara-CTP formation after Piceatannol preincubation.

 

Exposure of different-stage PC*3 prostate cancer (CaP) cells to Piceatannol also results in cell-type-specific downregulation of mTOR and its upstream and downstream effector proteins, AKT and eIF*4E-BP1.

 

Pays: China
N ° de modèle: -
Prix FOB: ( Negotiable ) Obtenir le dernier prix
Localité: Wuhan, China
Prix de commande minimale: -
Commande minimale: 1 Gram
Packaging Detail: -
Heure de livraison: -
Capacité de Fournir: 100 Kilogram per Month
Payment Type: Western Union, Money Gram, Other
Groupe de produits : -

Mots-clés correspondants Chongqing Tingyi Biotechnology Co, Ltd

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Clara < Chongqing Tingyi Biotechnology Co, Ltd >

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