Prix FOB
Obtenir le dernier prix46 ~ 54 / Box
|5 Box Minimum Order
Pays:
Ukraine
N ° de modèle:
Encephabol
Prix FOB:
46 ~ 54 / Box Obtenir le dernier prix
Localité:
Donetsk
Prix de commande minimale:
46 per Box
Commande minimale:
5 Box
Packaging Detail:
package must not exceed 2kg
Heure de livraison:
2 weeks by post or 2-5 days by EMS/DHL
Capacité de Fournir:
50 Box per Day
Payment Type:
D/P, Western Union, Money Gram
Groupe de produits :
Ukraine
Personne àcontacter Mr. Yuriy
17/91 Leninskiy ave., Donetsk, Donetsk
Â
Encephabol
®Â
Piritinol
hydrochloride **0 mgÂ
Other
ingredients: sodium karmelloza ***0, magnesium stearate, colloidal
silicon dioxide, sodium carboxymethyl starch, lactose monohydrate,
cellulose powder, quinoline yellow *0%, wax mountain glycol,
gelatin, gum arabic, wheat flour, titanium oxide (IV), white clay,
talc, sucrose.Â
Pharmacological
properties: encephabol improves the pathologically reduced
metabolism in the brain by increasing the capture and utilization
of glucose, the exchange of nucleic acids, as well as increased
release of acetylcholine at the synapse and the activation of
cholinergic neuronal transmission. Encephabol
stabilizes cell membranes and improves their function by preventing
the formation of free radicals. Encephabol
improves the rheological properties of blood: red blood cells
increases the elasticity and fluidity of the blood, increases the
ATP content in the membrane of red blood
cells. In
applying encephabol increases blood flow and increased oxygen
consumption in ischemic areas of the brain and activates the
exchange of glucose in the brain regions that previously defined
ischemic damage. Encephabol
contributes to the restoration of disturbed metabolic processes in
nerve tissue, improve mental performance and improve
memory.Â
After
oral administration, the drug is rapidly absorbed in the digestive
tract. Bioavailability
averaged *5% (****3%). Time
to reach maximum concentration after oral administration of **0 mg
encephabol is ****0 minutes. Binding
to plasma proteins - ****0%. Rapidly
metabolized in the liver with the formation of the main metabolites
- *-methyl**-hydroxy**-hydroxymethyl**-methylmercaptomethylperidine
and *-methylsulphenilmethylperidine. Conjugated
metabolites are primarily in the urine, about 5% - with the
feces. The
largest part of the dose was excreted within the first 4 hours
after ingestion. For
day 1 is derived approximately *4% of the dose.The
half-life is approximately 2.5 hours penetrates through the BBB,
the placental barrier in small amounts - into breast
milk. If
the kidney function of toxic concentrations in the body are not
attained.
Indications:
symptomatic treatment of chronic disorders of the brain function in
dementia syndromes with the following symptoms: impaired memory and
thinking, decreased concentration, fatigue, lack of incentives and
motivation, affective disorders.Â
Primary
degenerative dementia, dementia of vascular origin and mixed
forms. Symptomatic
treatment of chronic disorders of mental
disability. Post-traumatic
encephalopathy. Cerebral
atherosclerosis. The
consequences of encephalitis. Mental
retardation, tserebrastenichesky syndrome, encephalopathy in
children.Â
APPLICATION:
dose determined individually, taking into account disease severity
and patient response to treatment. The
average adult dose is **0 mg - 2 tablets of **0 mg or *0 ml
suspension (2 tablespoons). Multiplicity
of purposes - 3 times a day.Â
Infants
and children under 7 years are designated in the form of a
suspension: infants, beginning with the third day of life - to 1 ml
of suspension in the day in the morning for a month, starting from
the 2 nd month of life, this dose is increased by
1Â ml
of each week until a daily dose until it reaches the 5 ml (1
teaspoon) 1 year old and older, depending on the evidence - 1/**1
teaspoon suspension **3 times a day (from *0
to **0
mg / day) for children aged 7 years and older - **2 teaspoons of
suspension **3 times a day (from *0 to **0 mg /
day). Children
under the age of 7 years of age or older depending on the evidence
prescribed **2 tablets **3 times a day (from *0 to **0 mg /
day).Â
Take
medication during or after a meal. Tablets
swallowed whole, washed down with fluid.Patients
with sleep disorders, as well as children at increased excitability
is not recommended to take the medication in the
evening.Â
Clinical
improvement may occur within **4 weeks, but the optimal effect is
seen in ***2 weeks.Duration
of treatment for chronic diseases must be at least 8
weeks.Â
At
3 months, you should verify the presence of indications for further
treatment.Â
Contraindications:
Absolute - Hypersensitivity to piritinol to fructose (for the drug
in the form of suspension); relative - a history of kidney disease,
expressed by human liver and / or kidney disease; pronounced
changes in the composition of peripheral blood acute autoimmune
diseases such as systemic lupus
erythematosus, myasthenia
gravis.Â
SIDE
EFFECTS: when using the drug for indications and recommended doses,
side effects are unlikely.Â
Sleep
disturbance, at least - irritability, headache, dizziness, fatigue,
nausea, vomiting, diarrhea, at least - anorexia, taste
disturbances, stomatitis, transient increase of transaminases,
cholestasis, allergic reactions of varying severity (skin rash and
mucous membranes itching,
fever).Â
SPECIAL
NOTES: in patients with hypersensitivity to D-penicillamine may be
allergic reactions, since the latter is similar in chemical
structure piritinol (thiol groups).Â
Piritinol
crosses the placental barrier. The
results of the studies did not reveal the presence of the drug
teratogenic or embryotoxic action. In
breast milk gets a small amount of
piritinol. Decision
on the possible use of the drug during pregnancy and lactation
should be taken after an assessment of risk / benefit
ratio.Â
INTERACTION:
encephabol increases the severity of side effects of penicillamine,
gold, drugs, and sulfasalazine.Â
OVERDOSE:
shows increased symptom severity of side
effects. Conduct
gastric lavage, activated charcoal designate.Â
Storage
conditions: at temperatures up to ****5 °
C. Shelf
life - 5 years.
| Pays: | Ukraine |
| N ° de modèle: | Encephabol |
| Prix FOB: | 46 ~ 54 / Box Obtenir le dernier prix |
| Localité: | Donetsk |
| Prix de commande minimale: | 46 per Box |
| Commande minimale: | 5 Box |
| Packaging Detail: | package must not exceed 2kg |
| Heure de livraison: | 2 weeks by post or 2-5 days by EMS/DHL |
| Capacité de Fournir: | 50 Box per Day |
| Payment Type: | D/P, Western Union, Money Gram |
| Groupe de produits : | Nootropic agents |
